The centre promotes inter and multi- disciplinary approach for basic and need-based, applied research and efforts in bridging the gap between lab and society with respect to solid and liquid waste management. The current research at SCWRM involves novel technology and process development for solid waste and wastewater treatment, waste valorisation and resource recovery for circular economy and entrepreneurship development, microbiological and biotechnological investigations for development of value products/ formulations for industrial applications.

The centre has initiated several research projects on hematopoietic stem cells (HSCs), mesenchymal stem/stromal cells (MSCs), human pluripotent stem cells (hESCs), endometrial organoids, and bone and cartilage specific stem cells. SCSCR has state-of-art equipment to facilitate research of internationally accepted standards.

It's allied agenda of providing consultancy to organizations has also been kept in mind while marshaling the centre amongst industry and academia.

The center's focus areas include low-cost energy, affordable healthcare, and optical sensors. SCNN fosters interdisciplinary collaboration, partners with academia, industry, and government, and promotes awareness of nanotechnology's societal implications.

These techniques, supported by emerging artificial intelligence and machine learning domains, are an invisible aspect of modern clinical studies. SCMIA’s objective is to conduct translational biomedical research with a focus on medical imaging. The broader objectives of SCMIA are the development of novel computer-based image analysis methods and their application to a variety of clinical research studies as applicable to India population and in line with WHO’s SDGs and GoI’s Vikasit Bharat 2047 initiatives. SCMIA is a a translational research center that generates tools and techniques to help clinicians and surgeons in optimal decision-making and also help in early diagnosis and understanding of the underlying pathology.

Along with this SCAAI engages in interdisciplinary research to address pertinent issues that could involve a huge spectrum such as finance and banking to healthcare.

The Centre maintains a strong emphasis on policy studies, aiming to influence and inform policy making in the sector. SCHERPA aspires to evolve into a leading policy observatory in education by undertaking primary research as well as synthesizing research that is carried out in different parts of the country. It fosters policy dialogues that facilitates evidence-based policymaking with regular stakeholder consultations.

The center offers advanced degrees in life sciences, climate change studies, and sustainable development. A key focus of SCCCS' research is the often overlooked role of microbes in climate change mitigation and ecosystem services. The center is actively exploring ways to harness the potential of these microscopic organisms to combat climate change and promote sustainability.

SCUS is housed at the Symbiosis School of Economics, which offers the country's first programme - M.Sc. Economics with a specialisation in Urban Development. SCUS is housed at the Symbiosis School of Economics, which offers the country's first programme - M.Sc. Economics with a specialisation in Urban Development. 

The Symbiosis Centre for Research in Vaccines and Biologicals (SCRVB) shall be monitored by Symbiosis Center for Research and Innovation (SCRI), like all other Research Centres of SIU.